The 2022 U.S. Poker Open was held inside the PokerGO Studio at ARIA Resort & Casino from March 16-28, 2022. There were 12 events on the schedule, and Shannon Shorr, Justin Young, Adam Hendrix, Jeremy Ausmus, Alex Foxen, Chino Rheem, Erik Seidel, and Dylan Weisman all won U.S. Poker Open titles. Tamon Nakamura won two events early in the series, but Sean Winter won the final two events and was crowned the 2022 U.S. Poker Open Champion.